A Closer Look At Testosterone Deficiency

Testosterone deficiency, also known as hypogonadism, is a condition in which the testes are unable to produce enough testosterone to fulfill the body’s needs. Testosterone deficiency has many possible causes, including genetic abnormalities, injury to the testes, and being on certain medications. Normal aging also may play a role in the decline of male testosterone levels. It is also known as low testosterone.

The testes produce testosterone regulated by a complex chain of signals that begins in the brain. This chain is called the hypothalamic-pituitary-gonadal axis. The hypothalamus secretes gonadotropin-releasing hormone (GnRH) to the pituitary gland in spurts, which trigger the secretion of leutenizing hormone (LH) from the pituitary gland. This hormone stimulates the Leydig cells of the testes to produce testosterone. Normally, the testes produce 4-7 milligrams (mg) of testosterone each and every day.

more »